NR0B1 and familial pancreatic carcinoma: ScRNA-seq data also revealed that the known nuclear hormone receptor retinoic-acid-receptor-related orphan receptor gamma (RORγ) in pancreatic cancer stem cells which drives T cell differentiation is up-regulated during the progression of tumor and its pharmacological inhibitory effect leads to significant defect in the growth and increase in survival rate of pancreatic cancer (14).