Immunohistochemistry (IHC) analysis of N-terminal HIPK2 expression in human NSCLC showed negative staining (–) in 1.3% of 78 tumor samples, weak staining (+) in 9.0%, moderate staining (++) in 37.2%, and strong staining (+++) in 52.6% (Figure 2A, Supplementary Table 2). The gene discussed is HIPK2; the disease is neoplasm.