The novel HIPK2 isoform (110 kDa) was detected as the dominant HIPK2 isoform expressed in NSCLC cell lines (6/6) and tissues (13/24), and the HIPK2 isoform 1 (150 kDa) was only detected at lower levels in one of the six NSCLC cell line (H1975) and not detected in NSCLC tissues (0/24) (Supplementary Figures 2, 3). Here, HIPK2 is linked to non-small cell lung carcinoma.