Among the inflammasomes, NATCH, LRR, and PYD domain-containing protein 3 (NLRP3) is well characterized [2] and is associated with several human disorders such as Alzheimer's disease, obesity, rheumatoid arthritis, asthma, nonalcoholic fatty liver disease, and autoimmune encephalitis [3]. Here, NLRP3 is linked to Alzheimer disease.