There were no significant differences in clinicopathological factors, including the degree of differentiation, the diameter of tumor lesions, staging of the tumor, lymph node metastasis, relapse, age of menarche, age of marriage, times of fetation and times of abortion between patients with low-moderate and strong expression level of HPV58 E7, p16, and Ki-67. The gene discussed is MKI67; the disease is neoplasm.