IDH2 and central nervous system cancer: Patients with an IDH mutation gliomas had a significantly longer OS as compared with those with an IDH wildtype gliomas, with a median OS of 1.7, 6.3 and 8.0 years for patients with IDH wildtype, patients with IDH mutation only (astrocytic gliomas) and patients with IDH mutation plus 1p/19q codeletion (oligodendroglial gliomas), respectively 13.