We also discovered novel hub mRNAs, such as TAS2R3, VSTM2B, and HCRTR2, and other specific EAI-associated genes, such as ADCY6, ADCY1, and GLRA1, which have not been previously reported in female infertility but have been associated with important biological functions, including meiotic arrest and neuronal signaling (Mircea et al., 2007; Gentiluomo et al., 2017; Sethna et al., 2017; Dunietz et al., 2020). Here, ADCY1 is linked to female infertility.