LAMP2 and plasma cell myeloma: While patient derived LAMP-2-ANCA have previously been shown to bind epitopes within non-glycosylated sites of the protein backbone (12, 13), non-human mammalian protein expression systems, such as the mouse myeloma line used to produce the rhLAMP-2 used in the described ELISA, may induce glycosylation patterns not found in humans (18).