FLT3LG and neoplasm: The importance of FLT3L control of cDC1s in the tumor was further demonstrated in a recent murine model of pancreatic ductal adenocarcinoma (PDAC) where FLT3L and anti-CD40 combination therapy restored cDC1 infiltration, improved CD8+ T cell and Th1 control of tumor growth, and boosted responses to external radiation therapy (40, 41).