Notably, when the sorted CD14+ and CD14− DCs from the same patient were used in co-culture, the CD14+ DCs induced higher IL-17 production than their counterparts, whereas IFN-γ and IL-10 were induced with the same intensity (Figure 4C), indicating that CD14+ DCs are, at least in part, responsible for the Th17/Tc17 phenotype in patients with SCD. This evidence concerns the gene CD14 and Schnyder corneal dystrophy.