We found that in all tumor cell lines, the level of VEGF and MMP13 in culture medium was significantly higher after treatment with VX765 compared to Nigericin and LPS/Nigericin and untreated controls (p < 0.05) (Figure 7, Supplementary Figures 6, 7, Supplementary Tables 6, 7). Here, MMP13 is linked to neoplasm.