Because mCD40-LMP1 drives an autoimmunity phenotype that leads to overt pathology in the context of the autoantigen collagen (70), we hypothesized that LMP1 may enhance the onset of autoimmunity in conjunction with molecular mimicry between EBNA-1 and the SLE-associated autoantigen, Sm (86). The gene discussed is PDLIM7; the disease is systemic lupus erythematosus.