Oxidative stress, fatty acid, and ceramide metabolism were partially corrected by fenretinide in CFTR KO pig primary airway cells, extending recent data confirming its involvement in ceramide metabolism obtained from CFTR KO mice (Youssef et al., 2020c) and CF model cell lines (Guilbault et al., 2009; Garic et al., 2017). The gene discussed is CFTR; the disease is cystic fibrosis.