E2F1 and lung cancer: They were FUT8, CCNE1, E2F1, ARHGAP11A, ARHGEF7, RUNX1T1, ACADVL and FES. Among them, cell cycle related oncogenes CCNE1 (Moroy and Geisen, 2004) and E2F1 (Poppy Roworth et al., 2015) were high expression and predictive of poor patient survival in lung cancer.