ENTPD1 and type 2 diabetes mellitus: On the other hand, low levels of CD4+ IL-17+ cells in overweight and obese T2D patients positively correlates with glucose and HbA1c (Cortez-Espinosa et al., 2015), whereas a subpopulation of SupTh17 NTPDase1/CD39+ cells negatively correlates with glycemia and HbA1c.