NCF4 and acute lymphoblastic leukemia: Furthermore, phosphorylated p40 (PHOX) inhibits oxidase if added before or after full activation of the enzyme, thus they have postulated that phosphorylation of p40 (PHOX) in threonine 154 leads to an inhibitory conformation that changes the balance towards an inhibitory role and blocks oxidase activation in such a way that in our study we found that for the rs1883112 polymorphism of the NCF4 gene, the heterozygous allele shows a risk effect for ALL (OR = 2.1267 (CI = 1.0020–4.5138), p = 0.04.