CXCL10 and Middle East respiratory syndrome: This pathway may temporally regulate CXCL10 to delay and sustain its expression during MERS, potentially enhancing viral pathogenicity as evidenced by the positive association of MERS severity with circulating CXCL10 levels (Kim et al., 2016; Min et al., 2016; Hong et al., 2018; Shin et al., 2019).