Moreover, infection with lethal strains of SARS-CoV demonstrated worse lung pathology and higher levels of induction of inflammatory chemokines, such as Cxcl10 and Ccl2, than infection with non-lethal SARS-CoV strains that replicated to similar or even higher levels in the lung (Rockx et al., 2009). This evidence concerns the gene CXCL10 and infection.