The cytokine storm in COVID-19 results in IL-6 dependent alterations in the expression of vascular endothelial growth factor and E-cadherin expression on endothelial cells contributing to vascular leakage and pulmonary hypertension, and respiratory distress in COVID-19 patients (Lukan, 2020; Moore and June, 2020). This evidence concerns the gene VEGFA and COVID-19.