In rodents, Cyfip1 manipulation has strong anatomical, cellular, and physiological consequences that overlap mechanistically with cell signaling pathways employed by other genes relevant to intellectual disability, autism, and schizophrenia (Bozdagi et al., 2012; Dominguez-Iturza et al., 2019; Fricano-Kugler et al., 2019; Silva et al., 2019). Here, CYFIP1 is linked to Intellectual disability.