They found that GLICO tumors had significantly higher expression of key GBM-related genes including SRY-box Transcription Factor 4 (SOX4), Karyopherin Subunit Alpha 2 (KPNA2) and Brevican (BCAN), a marker for GBM invasiveness (Darmanis et al., 2017). The gene discussed is KPNA2; the disease is glioblastoma.