Furthermore, upregulated TRPV1 expression and function in lung afferents is characteristic of such pathologic conditions as chronic cough, asthma, and pulmonary inflammation of various etiologies (Trevisani et al., 2004; Kichko and Reeh, 2009; Choi et al., 2018; Zhang et al., 2018). Here, TRPV1 is linked to asthma.