miR-93-5p, which was reported to promote the proliferation of NSCLC cells and is indicative of a poor prognosis, was found to enhance the transcription of several oncogenic genes, such as HMGA2, E2F2, KIF23, POLQ, PRR11, GINS4, WNK3, LYPD6, KIF14, RAB3B and downregulate the expressions of tumor suppressors such as ATP1A2 and CYBRD1. The gene discussed is HMGA2; the disease is non-small cell lung carcinoma.