Several studies demonstrate that the incidence of hyperlipidemia is higher in elderly people (1259/1657, 76%, mean age 69 years) than in young people (203/494, 41%, mean age 29 years); this difference was attributed to age-associated declines in ribosome coverage in the vicinity of start codons and increases near stop codons, alterations in expression of genes associated with lipid metabolism, loss of hepatic LDL receptors, and decreases in sex hormone levels [36, 37]. Here, LDLR is linked to hyperlipidemia.