ALKBH5 and glioblastoma: Furthermore, Somasundaram’s group performed a comparison of expression levels of METTL3/METTL14 and FTO/ALKBH5 in multiple GBM transcriptome and pan caner datasets, and found that METTL3 is significantly upregulated in the majority of tumors compared with METTL14, FTO, and ALKBH5.