Furthermore, Somasundaram’s group performed a comparison of expression levels of METTL3/METTL14 and FTO/ALKBH5 in multiple GBM transcriptome and pan caner datasets, and found that METTL3 is significantly upregulated in the majority of tumors compared with METTL14, FTO, and ALKBH5. The gene discussed is METTL14; the disease is glioblastoma.