Immunofluorescent triple labelling for GRID2, IBA1 and tau on enthorinal allocortex and temporal isocortex of 8 CTR and 12 AD donors showed that GRID2 cells were abundant in AD samples with increasing amounts of tau pathology and localized to regions with tau pathology (Fig. 4f, S8c–f). The gene discussed is MAPT; the disease is Alzheimer disease.