AS602801 + VCR declined the expression of p‐JNK (Figure 7B,C) and CX43 (Figures 7B,D,8A) proteins in glioma cell xenograft, whereas the expression of CASP‐3 was increased by the AS602801 + VCR treatment (Figure 7B,E). This evidence concerns the gene MAPK8 and central nervous system cancer.