Thus, all these data demonstrated that the TMPRSS2 is mostly enriched in the regulation of viral entry, protein processing, serine‐type peptidase activity, prostate gland cancer cell expression, different complex(es) formation, diseases including influenza and carcinoma, and misregulation of pathways in prostate cancer, influenza A, and transcription in cancer. The gene discussed is TMPRSS2; the disease is influenza.