Altogether, these data suggest that TMPRSS2, with its high expression and usage of TMPRSS2‐001 and TMPRSS2‐201 containing both SRCR_2 and Trypsin (Tryp_SPc) in PRAD, should play important roles in tumorigenesis and COVID‐19 viral entry into PRAD tumour tissues. The gene discussed is TMPRSS2; the disease is neoplasm.