ALOX5 and infection: Furthermore, we found a correlation between the IVI-induced and MT-affected gene networks and lipid mediator response, whereby AA-derived lipid mediators and DHA-derived lipid mediators were positively correlated with the immune response induced by the viral infection, and lipid mediators in the 5-LOX or 15-LOX pathway associated with lung tissue-specific genes tended to be decreased by infection and improved by MT.