CD74 and neoplasm: We report that male MG and intMoMΦ from the tumor-bearing hemispheres show higher expression of genes coding for MHCII components and Cd74. Evaluation of the Cd74 and MHCII genes by qPCR in primary MG cultures from male and female brains shows higher expression of these genes in male MG in cocultures with GL261 cells and under basal conditions.