The expression of Hp, Emilin2, Sell, and Gda, the markers suggested in recent meta-analysis of bulk RNA-seq data sets, and validated at RNA and protein levels23, was found in the fraction of Mo (Ly6c2hi and Ccr2hi; Supplementary Fig. 5e). Expression of  Tgm2 and Gpnmb, previously reported as the genes commonly upregulated by GAMs across different glioma animal models and in a bulk RNA-seq of patient-derived samples3, was limited to the small fraction of Mo/MΦ (Supplementary Fig. 5e). This evidence concerns the gene EMILIN2 and central nervous system cancer.