Among TME-infiltrating male MG, we found cluster MG8 characterized by a high expression of genes encoding proliferation-related proteins (Stmn1, Tubb5, Tuba1b, Cdk1, and Top2a), which is consistent with the observed proliferation of MG within glioma TME, as previously reported6,39. The gene discussed is CDK1; the disease is central nervous system cancer.