Among TME-infiltrating male MG, we found cluster MG8 characterized by a high expression of genes encoding proliferation-related proteins (Stmn1, Tubb5, Tuba1b, Cdk1, and Top2a), which is consistent with the observed proliferation of MG within glioma TME, as previously reported6,39. This evidence concerns the gene STMN1 and central nervous system cancer.