TNF and Parkinson disease: Similarly, no associations of the genotypes of implicated functional variant (rs1800693) with PD risk (OR 1.00 per TNF-inhibiting allele; 95% CI 0.98–1.02) or age at onset (0.05 years of increase per TNF-inhibiting allele; 95% CI −0.13 to 0.24) were observed, despite strong associations of this SNP with other inflammatory traits (figure 3).