PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Individuals who carry the PNPLA3 rs738409 gene polymorphism have a greater risk of developing NAFLD [44]; in addition, a meta-analysis showed that the PNPLA3 rs738409 gene polymorphism is more prevalent in non‐obese NAFLD patients than that in obese NAFLD patients [41].