CDK1 and colorectal carcinoma: To elucidate the possible effect of CDK1 on CRC progression, IHC was performed to analyze the expression of CDK1 in paraffin-embedded tissues of 108 CRC patients from the Department of Pathology (Fig. 4g), and the associations of CDK1 level with patient clinicopathological features were examined, which indicated a high CDK1 expression within the CRC and had an aggravating effect on CRC.