In an analysis of data from 2002 to 2009, the immune status of participants initiating treatment in a clinic participating in a multicohort collaboration spanning 6 continents (International epidemiological Databases to Evaluate AIDS and ART Cohort Collaboration) remained low: median CD4 cell counts was ≤200 cells/mL in low-income countries and ≤ 300 cells/mL in high-income countries [35]. Here, CD4 is linked to AIDS.