CRYAB and cancer: Several publications have recently claimed that CRYAB overexpression is significantly associated with poor prognosis in various types of cancer, while other studies have reported that the connection is not significant.[5–7,9–22] Therefore, we conducted this meta-analysis to evaluate the correlation between high CRYAB expression and the prognosis of human solid tumors, and to clarify the clinical value of CRYAB as a potential prognostic indicator and therapeutic target for human solid tumors.