By contrast, pronounced C5aR1 expression in a higher number of tumour samples was observed in all types of thyroid carcinomas, small-cell lung cancer, hepatocellular and cholangiocellular carcinomas, pancreatic adenocarcinomas, gastrointestinal stromal tumours, renal clear cell carcinomas and ovarian and endometrial cancer. Here, C5AR1 is linked to pancreatic adenocarcinoma.