A mouse abdominal aortic aneurysm model wasestablished by embedding an Ang II pump (1000 ng/kg/min) in ApoE-/- mice.Ang II activated monocytes to express CXCR2(CD45+CD11+bF4/80+) during AAA formation. This evidence concerns the gene CXCR2 and abdominal aortic aneurysm.