CD4 and cancer: Among them, the CDCA3 expression was correlated with tumor purity in 22 cancer types, the CDCA3 expression was also associated with the infiltrating levels of B cells in 13 cancer types, CD8+ T cells in 11 cancer types, CD4+ T cells in 15 cancer types, macrophages in 17 cancer types, neutrophils in 12 cancer types, and dendritic cells in 14 cancer types (Figure 4 and Figure S2).