According to the expression of ATG4D and MAP1LC3C in GC, the gastric cancer patients were divided into four groups: ATG4D high expression - MAP1LC3C high expression (HH), ATG4D low expression - MAP1LC3C low expression (LL), ATG4D high expression - MAP1LC3C low expression (HL) and ATG4D low expression - MAP1LC3C high expression (LH). The gene discussed is ATG4D; the disease is gastric cancer.