Belian et al. (2010) studied the effect of YB-1 on the conversion of miRNA expression in drug-sensitive GC and found that miR-1275 expression was up-regulated after inhibiting YB-1 expression. Mei et al. (2019) found that MicroRNA-1275 can regulate vimentin and E-cadherin through JAZF1, thereby inhibiting cell migration and invasion in GC. Feng et al. (2018) showed that down-regulated serum miR-126 is associated with aggressive progression and poor prognosis of gastric cancer. Li, Wang & Wang (2018) found that miR-126 functions as a Tumor Suppressor by Targeting SRPK1 in Human Gastric Cancer. The gene discussed is YBX1; the disease is gastric cancer.