It is generally believed that physiological functions of apoCIII is to mediate the triglyceride(TG)-rich lipoprotein metabolism thereby maintaining the plasma TG homeostasis and high plasma levels of apoCIII are positively associated with plasma TG and increases the risk of ischemic heart disease (Huff and Hegele, 2013; Norata et al., 2015; Ramms and Gordts, 2018). Here, APOC3 is linked to coronary artery disorder.