KIT and Hepatic fibrosis: In carbon tetrachloride (CCl4)-induced liver fibrosis mice, the differentiation potential of circulation of endothelial progenitor cells (EPCs) is attenuated due to the impairment of the endothelial lineage differentiation potential of bone marrow-C-kit+, Sca-1+, and Lin–(BM-KSL) cells (Shirakura et al., 2011).