Recently, the use of QFT-P in combination with the detection of IFN-γ responses to recombinant Mycobacterium smegmatis heparin-binding hemagglutinin (hereafter called “rmsHBHA IGRA”) as an additional stimulation antigen has shown promise to stratify TB cases by stage of infection and progression to disease (23–27), and to monitor TB treatment outcomes (28). The gene discussed is IFNG; the disease is infection.