Overall, neutrophil and lymphocyte percentages directly impacted IFN-γ responsiveness to TB-specific antigens: QFT-P and rmsHBHA IFN-y levels and positivity rates were significantly higher in patients with low neutrophil (Figures 3A, B) or with high lymphocyte proportions (Figures 3C, D). The gene discussed is IFNG; the disease is tuberculosis.