A synthetic pelargonidin (Mt-P) transactivates AhR, and has been shown, in HFD-fed C57BL/6J mice, to attenuate body weight gain, intestinal and liver inflammation, and ameliorate insulin sensitivity, while worsening liver steatosis, of which were abrogated by gene ablation of AhR (232). Here, AHR is linked to Hepatic steatosis.