In a similar study of other animals, adult rats regulated with chronic constant light exhibited depressive and anxiety behavior as grooming in the open-field test and an anhedonia-like expression in a sucrose consumption test and with decreasing cellular activation visualized by c-Fos immunohistochemistry in the biological clock nerve center, the suprachiasmatic nucleus (SCN) (Tapia-Osorio et al., 2013). The gene discussed is CLOCK; the disease is Anxiety.