HIF1A and Ewing sarcoma: To further assess the link between HACE1 and HIF1α in human tumors, tissue microarrays (TMAs) consisting of WT (9 cases) and different childhood sarcomas (18 cases, including 5 Ewing sarcoma cases, 3 alveolar rhabdomyosarcoma cases, 4 embryonal rhabdomyosarcoma cases, and 6 synovial sarcoma cases, which were analyzed collectively due to the limited case numbers) were subjected to IHC for HACE1 and HIF1α expression.