While the TAp63α isoform was highly expressed in wild-type kidney, the TAp63δ showed an overexpression in wild-type bones, and kidney and spleen tumours (Fig. 5c), and variable expression in OS (Fig. 5d) from flTP53R167H pigs, indicating that the TP53 mutation has a tissue- and tumour-specific effect on the TAp63δ isoform expression. This evidence concerns the gene TP53 and neoplasm.