CCR2 and cancer: In a phase II clinical trial for patients with cancer metastatic to the bone, an anti-CCR2 antibody (MLN1202) caused considerable reduction in urinary N-telopeptide (uNTX) values after 43 days of treatment in for 14 out of 43 patients with bone metastasis [128] (ClinicalTrials.gov ID: NCT01015560).