ANXA5 and lung cancer: On the other hand, there was remarkable increase in the percentage of cells in both early (Annexin V + /PI-) and late (Annexin V + /PI +) apoptosis in human lung cancer cells pretreated with 5 μg/mL of 0.4 M NaCl peptide for 6–24 h following with further 24 h treatment of 5 μM cisplatin (Fig. 3e).