LY6D and colorectal cancer: We also found that the eSNP rs3808491 (C/T, linear regression, t test, FDRinteraction = 7.23 × 10−6, FDRgentoype = 1) forms an inflammation-dependent cis-eQTL with its eGene, LY6D, which is upregulated in (colorectal) cancer tissue23.