To determine the effect of Oxali and related drugs on gene expression in PCa cell lines used in our previous study (22), Myc-CaP cells were treated with different drugs at doses that induce no more than 10% cell death, and vital cells (SI Appendix, Fig. S1 A and B) were analyzed by whole genome RNA sequencing (RNA-seq) and assay for transposase-accessible chromatin (ATAC-seq) (26). This evidence concerns the gene MYC and posterior cortical atrophy.