EP300 and neoplasm: Of note, p300 or IFNγR2 ablation had little effect on tumor-infiltrating effector CD8+ T cells, whose numbers were similarly increased after Oxali + anti–PD-L1 treatment in p300- or IFNγR2-expressing and nonexpressing tumors (Fig. 7 M and N and SI Appendix, Fig. S16 C–H).