CREBBP and cancer: To gather information about p300 and CBP in human cancer, we examined The Cancer Genome Atlas (TCGA) dataset and found significant correlations between EP300 or CBP mRNAs and genes identified by our integrative RNA-seq and ATAC-seq analyses, including RELA, STAT1, NFKB1, IFNGR2, and NLRC5 (Fig. 5 A and B and SI Appendix, Fig. S7A).