Alijanipour et al. [29] showed that early postoperative and late chronic PJI had different thresholds of ESR and CRP, with the late chronic PJI values being higher than the early postoperative PJI values, in a retrospective review of 1962 patients who underwent revision arthroplasty for aseptic prosthetic failure (n=1689) or first onset of PJI (n=273) between 2000 and 2009. The gene discussed is CRP; the disease is juvenile polyposis syndrome.